Research library / Compounds
A copper-binding tripeptide first reported in human plasma in 1973.
GHK-Cu is the copper complex of a three-amino-acid peptide: glycine, histidine and lysine. The peptide was first reported in human plasma in 1973, and it binds copper strongly, which is why the copper complex is the form researchers usually study. Prism Labs supplies it as a lyophilized vial.
01
What is GHK-Cu made of?
The peptide is glycyl-L-histidyl-L-lysine. In the reference copper complex, one copper ion is bound per peptide; the record lists the formula C14H22CuN6O4 and a molecular weight of 401.91 g/mol (PubChem CID 165429100).
Other copper-to-peptide ratios have their own database records. The identity result on your COA is what confirms the supplied form.
Sources: [2] PubChem · reference structure
02
Where to buy GHK-Cu
GHK-Cu is sold direct by Prism Labs at prismlabs.store, in 50mg and 100mg vials from $34.99 per vial. The latest published lab report, tested October 26, 2026, measured 99.86% purity. Every lot’s certificate of analysis is on the product page, with a link to verify it with the testing lab.
Orders placed before 4:30 PM CT ship the same day, seven days a week, when the size is in stock. Standard shipping is free over $125. Packs of 2 or more vials are discounted, up to 18% off.
See GHK-Cu sizes, prices and lab reports · How to vet any peptide supplier
03
Where did GHK-Cu come from?
In 1973, Loren Pickart reported a tripeptide in human plasma that prolonged the survival of cultured liver cells. Later work identified it as glycyl-histidyl-lysine and showed that it binds copper(II).
Research has since moved from cell survival to tissue remodeling and, more recently, to large gene-expression datasets.
Sources: [1] Nature New Biology · 1973 · [3] Journal of Biomaterials Science, Polymer Edition · 2008 · [5] International Journal of Molecular Sciences · 2018
04
What has GHK-Cu been studied for?
Most published work comes from cell and animal models and from formulation studies:
- Tissue remodeling and collagen-related signaling.
- Skin-cell research, including work on cosmetic formulations.
- Genome-wide expression data, which a 2018 review used to map genes associated with the peptide.
These are observations in laboratory models. They are not evidence about any use in people.
Sources: [3] Journal of Biomaterials Science, Polymer Edition · 2008 · [4] BioMed Research International · 2015 · [5] International Journal of Molecular Sciences · 2018
05
Where else does GHK-Cu appear?
GHK-Cu is also a component of two Prism Labs blends: Glow-70, with two other peptides, and Klow-80, which adds KPV. How the two blends differ: Klow vs Glow.
06
How is GHK-Cu supplied and stored?
GHK-Cu ships as a lyophilized (freeze-dried) powder in 50 mg or 100 mg vials. The powder is stable at room temperature in transit. For lab use it is reconstituted with bacteriostatic water such as Prism H2O.
Concentration is content divided by volume: 50 mg in 5 mL gives 10 mg per mL. The reconstitution calculator handles other combinations.
For storage before and after reconstitution, see how to store lyophilized peptides.
07
How do I verify GHK-Cu batches?
Every lot has its own certificate of analysis from an independent lab. Read three results separately:
- Identity: confirms the expected compound was detected.
- Purity: the share of the measured material that is the intended compound.
- Content: the amount measured, compared with the label.
Then match the lot number on your vial or bottle to the report, and use the report’s verification link to confirm it with the testing lab. Step by step: how to read a peptide COA.
A little more clarity
Questions, answered
What is GHK-Cu?
The copper complex of the tripeptide glycyl-histidyl-lysine. It was first reported in human plasma in 1973 and is studied in tissue-remodeling and skin-cell research.
Where can I buy GHK-Cu?
From Prism Labs at prismlabs.store, in 50mg and 100mg vials from $34.99 per vial. Each lot’s certificate of analysis is published on the product page.
Is it the same copper peptide used in skincare?
Skincare products often use the same copper tripeptide inside finished formulas. Research-grade powder is a different product, documented by its own COA.
Why does it contain copper?
The tripeptide binds copper(II) strongly, and most research uses the copper-bound form.
Does it come as a nasal spray?
No. Prism Labs supplies it as 50 mg and 100 mg lyophilized vials, each lot with its own COA. How the two formats differ in general: peptide nasal spray vs vial.
Is it for human use?
No. Prism Labs sells it for laboratory research use only.
Follow the evidence
Sources & reading notes
Open the original record for its methods and limitations. The sources below do not certify the supplied product or its finished formulation.
- Nature New Biology · 1973 ↗
Original report of the tripeptide in human plasma; cell-culture study.
- PubChem · reference structure ↗
The 1:1 copper complex referenced in the product specifications; not a batch measurement.
- Journal of Biomaterials Science, Polymer Edition · 2008 ↗
Review of the tripeptide in tissue-remodeling research.
- BioMed Research International · 2015 ↗
Review of skin-cell and cellular-pathway research.
- International Journal of Molecular Sciences · 2018 ↗
Review of gene-expression data.
Prepared by Prism Labs from the linked source records and public product documentation. Research context only; not a preparation protocol or a claim about outcomes. Send a source correction.




