Prism Labs

What is BPC-157 peptide?

Research library / Compounds

A fifteen-residue fragment first described in gastric-juice research in the early 1990s.

BPC-157 is a synthetic peptide of 15 amino acids, GEPPPGKPADDAGLV. It is a fragment of a larger protein that a research group in Zagreb described in human gastric juice in the early 1990s. Prism Labs supplies it as a lyophilized vial.

01

What is BPC-157 made of?

The sequence of BPC-157 is Gly–Glu–Pro–Pro–Pro–Gly–Lys–Pro–Ala–Asp–Asp–Ala–Gly–Leu–Val. The reference structure has the molecular formula C62H98N16O22 and a molecular weight of 1419.5 g/mol (PubChem CID 9941957).

Papers often call it a stable gastric pentadecapeptide. Pentadecapeptide simply means a chain of 15 amino acids.

Sources: [3] PubChem · reference structure · [4] Frontiers in Pharmacology · 2021

02

Where to buy BPC-157

BPC-157 is sold direct by Prism Labs at prismlabs.store, in 5mg and 10mg vials from $34.99 per vial. The latest published lab report, tested October 26, 2026, measured 99.73% purity. Every lot’s certificate of analysis is on the product page, with a link to verify it with the testing lab.

Orders placed before 4:30 PM CT ship the same day, seven days a week, when the size is in stock. Standard shipping is free over $125. Packs of 2 or more vials are discounted, up to 18% off.

See BPC-157 sizes, prices and lab reports · How to vet any peptide supplier

Every lot ships with its own certificate of analysis.

03

Where did BPC-157 come from?

In 1993, Predrag Sikirić’s group in Zagreb described a protein from human gastric juice and proposed a role for it in protecting the stomach lining. Follow-up papers in 1994 studied a 15-amino-acid fragment of that protein: the sequence sold under this name today.

Most published research still comes from that group and its collaborators. A 2025 review notes that most of the evidence comes from animal studies, and a 2025 literature and patent review traces how the research and patents developed.

Sources: [1] Journal of Physiology (Paris) · 1993 · [2] Life Sciences · 1994 · [7] Current Reviews in Musculoskeletal Medicine · 2025 · [8] Pharmaceuticals · 2025

04

What has BPC-157 been studied for?

The literature is large and mostly preclinical. The main themes:

  • Gastrointestinal research in rodent models, where the peptide was first studied.
  • Tendon and ligament research, including a 2011 study of tendon cells in culture.
  • Blood-vessel growth factors and related signaling.

These are observations in laboratory models. They are not evidence about any use in people.

Sources: [2] Life Sciences · 1994 · [5] Journal of Applied Physiology · 2011 · [6] Current Pharmaceutical Design · 2018

05

BPC-157 vs TB-500

These two are often sold and studied together, but they are unrelated molecules. BPC-157 is a fragment of a gastric-juice protein with one well-defined sequence. TB-500 is named after thymosin beta-4, a 43-amino-acid actin-binding protein found in most cells, and the name is used for more than one thymosin-derived sequence. Their research themes differ too: gastrointestinal and tendon models on one side, blood-vessel development and cell migration on the other.

Prism Labs sells each on its own and together as the Wolverine Stack (BPC + TB). Side by side: BPC-157 vs TB-500.

Sources: [1] Journal of Physiology (Paris) · 1993 · [9] PNAS · 1981 · [10] Annals of the New York Academy of Sciences · 2007

06

Is BPC-157 FDA-approved?

No. BPC-157 is not an FDA-approved drug. In October 2026, HHS said it does not intend to act against state-licensed pharmacies and licensed physicians that compound it for a patient with a prescription, under set conditions. That is not approval, and it does not cover research-use vials like ours. Details: what the HHS peptide policy changed.

07

How is BPC-157 supplied and stored?

BPC-157 ships as a lyophilized (freeze-dried) powder in 5 mg or 10 mg vials. The powder is stable at room temperature in transit. For lab use it is reconstituted with bacteriostatic water such as Prism H2O.

For a vial, concentration is content divided by volume: 10 mg in 2 mL gives 5 mg per mL. The reconstitution calculator handles other combinations.

For storage before and after reconstitution, see how to store lyophilized peptides.

08

How do I verify BPC-157 batches?

Every lot has its own certificate of analysis from an independent lab. Read three results separately:

  • Identity: confirms the expected compound was detected.
  • Purity: the share of the measured material that is the intended compound.
  • Content: the amount measured, compared with the label.

Then match the lot number on your vial or bottle to the report, and use the report’s verification link to confirm it with the testing lab. Step by step: how to read a peptide COA.

A little more clarity

Questions, answered

What is BPC-157?

A synthetic 15-amino-acid peptide (GEPPPGKPADDAGLV), a fragment of a protein first described in gastric-juice research in the early 1990s. It has been studied mostly in animal and cell models.

Where can I buy BPC-157?

From Prism Labs at prismlabs.store, in 5mg and 10mg vials from $34.99 per vial. Each lot’s certificate of analysis is published on the product page.

Is BPC-157 a peptide?

Yes. It is a pentadecapeptide, a chain of 15 amino acids.

What is the difference between BPC-157 and TB-500?

They are unrelated molecules: one is a fragment of a gastric-juice protein, the other is named after thymosin beta-4. They are often studied side by side and sold together.

Does it come as a nasal spray?

No. Prism Labs supplies it as 5 mg and 10 mg lyophilized vials, each lot with its own COA. How the two formats differ in general: peptide nasal spray vs vial.

Is it for human use?

No. Prism Labs sells it for laboratory research use only.

Follow the evidence

Sources & reading notes

Open the original record for its methods and limitations. The sources below do not certify the supplied product or its finished formulation.

  1. Journal of Physiology (Paris) · 1993 ↗

    Description of the gastric-juice protein and the group’s early hypothesis.

  2. Life Sciences · 1994 ↗

    Early study of the 15-residue fragment in rodent gastric models.

  3. PubChem · reference structure ↗

    The structure referenced in the product specifications; not a measurement of the supplied batch.

  4. Frontiers in Pharmacology · 2021 ↗

    Review of the research in wound models.

  5. Journal of Applied Physiology · 2011 ↗

    Tendon cells in culture.

  6. Current Pharmaceutical Design · 2018 ↗

    Review of growth-factor and blood-vessel research.

  7. Current Reviews in Musculoskeletal Medicine · 2025 ↗

    Narrative review of the evidence and its limits.

  8. Pharmaceuticals · 2025 ↗

    Literature and patent review.

  9. PNAS · 1981 ↗

    Sequence of thymosin beta-4, the protein the other peptide is named after.

  10. Annals of the New York Academy of Sciences · 2007 ↗

    Thymosin beta-4 in coronary blood-vessel development in mice.

Prepared by Prism Labs from the linked source records and public product documentation. Research context only; not a preparation protocol or a claim about outcomes. Send a source correction.

From reading to verification

Match the material to its record.

Check the product, size and lot. Then read identity, purity and measured content as separate results.