What is 5-amino-1MQ?

01

What is 5-amino-1MQ made of?

5-amino-1MQ is a quinolinium ion: a two-ring aromatic structure with a methyl group on the ring nitrogen and an amino group at position 5. The reference record lists the ion as C10H11N2+ with a mass of 159.21 g/mol (PubChem CID 950107).

Because it carries a permanent positive charge, it is supplied as a salt, and the counter-ion adds to the weight. Check the formula on the COA before doing concentration math.

Sources: [1] PubChem · reference structure

02

Where to buy 5-amino-1MQ

5-amino-1MQ is sold direct by Prism Labs at prismlabs.store, in 50mg vials at $59.99 per vial. The latest published lab report, tested October 26, 2026, measured 99.86% purity. Every lot’s certificate of analysis is on the product page, with a link to verify it with the testing lab.

Orders placed before 4:30 PM CT ship the same day, seven days a week, when the size is in stock. Standard shipping is free over $125. Packs of 2 or more vials are discounted, up to 18% off.

See 5-amino-1MQ sizes, prices and lab reports · How to vet any peptide supplier

03

What NNMT does

Nicotinamide N-methyltransferase (NNMT) moves a methyl group from S-adenosylmethionine (SAM) onto nicotinamide, producing 1-methylnicotinamide. That reaction touches both the cell’s supply of methyl groups and the breakdown of nicotinamide, a building block of NAD+.

NNMT has drawn interest as a research target; a 2021 review covers how it works and the inhibitors designed against it.

Sources: [2] RSC Medicinal Chemistry · 2021 · [3] Biochemical Pharmacology · 2018

04

Where did 5-amino-1MQ come from?

5-amino-1MQ belongs to a series of methylquinolinium NNMT inhibitors described in 2018 by a group at the University of Texas Medical Branch. In cultured fat cells, the inhibitors lowered the enzyme’s product and raised cellular levels of SAM and NAD+; the paper also tested one in mice fed a high-fat diet.

A 2019 study from the same group examined an NNMT inhibitor and muscle stem cells in aged mice.

Sources: [3] Biochemical Pharmacology · 2018 · [4] Biochemical Pharmacology · 2019

05

What has 5-amino-1MQ been studied for?

Work so far is in enzymes, cells and mice:

• NNMT activity, and selectivity against related methyltransferases.
• Cellular levels of SAM, nicotinamide and its methylated product.
• Fat-cell and muscle-stem-cell models.

These are observations in laboratory models. They are not evidence about any use in people.

Sources: [3] Biochemical Pharmacology · 2018 · [2] RSC Medicinal Chemistry · 2021 · [4] Biochemical Pharmacology · 2019

06

How is 5-amino-1MQ supplied and stored?

5-amino-1MQ ships as a dry powder in a 50 mg vial and is dissolved in bacteriostatic water such as Prism H2O for lab use.

Concentration is content divided by volume: 50 mg in 5 mL gives 10 mg per mL. Use the salt weight from the COA, not the mass of the ion alone. The reconstitution calculator handles other combinations.

For storage before and after reconstitution, see how to store lyophilized peptides.

07

How do I verify 5-amino-1MQ batches?

Every lot has its own certificate of analysis from an independent lab. Read three results separately:

• Identity: confirms the expected compound was detected.
• Purity: the share of the measured material that is the intended compound.
• Content: the amount measured, compared with the label.

Then match the lot number on your vial or bottle to the report, and use the report’s verification link to confirm it with the testing lab. Step by step: how to read a peptide COA.